Al- Ka'ba in Makkah was the first house put by Allah (SWT) for all human beings (Aal Imran ; 96), that is why many prophets were born and lived in or near that area. It is also the place of the world gathering of Hajj. People come from all over the world to Makkah for Hajj and Umra. Prophets used to teach and guide them in every possible way.
The Arabian Peninsula is the central area of the whole world.