The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system. Blood provides the body with oxygen and nutrients, as well as assisting in the removal of metabolic wastes. In humans, the heart is located between the lungs, in the middle compartment of the chest.In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles.